Title : Is there a prostaglandin involvement in the positive inotropic action of histamine in isolated pregnant rat uterus, apparently mediated via H1-receptors activation?

Pub. Date : 1987 Aug

PMID : 3477825






1 Functional Relationships(s)
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1 In addition, the positive uterine inotropism evoked by histamine in the ME region of preparations isolated at the 16th day of pregnancy, was significantly reduced by an antagonist of phospholipase A2 (mepacrine, 10(-4) M) as well as by acetylsalicylic acid (ASA at 10(-4) M), an inhibitor of cyclooxygenase. Histamine phospholipase A2 group IB Rattus norvegicus