Pub. Date : 2021 Nov 5
PMID : 34769439
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In addition, IL-4 and IL-13 stimulate tyrosine phosphorylation of insulin receptor substrate-1 (IRS-1). | Tyrosine | interleukin 13 | Mus musculus |
| 2 | Prolonged treatment with these cytokines leads to increased IRS-1 abundance, which, in turn, amplifies IL-4- and IL-13-stimulated IRS-1 tyrosine phosphorylation. | Tyrosine | interleukin 13 | Mus musculus |
| 3 | Through signaling crosstalk between IL-4/IL-13 and insulin, a hormone routinely included in mammary cultures, IRS-1 tyrosine phosphorylation is further enhanced. | Tyrosine | interleukin 13 | Mus musculus |