Title : ABCC5 facilitates the acquired resistance of sorafenib through the inhibition of SLC7A11-induced ferroptosis in hepatocellular carcinoma.

Pub. Date : 2021 Dec

PMID : 34768109






1 Functional Relationships(s)
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1 Importantly, activation of PI3K/AKT/NRF2 axis was essential for sorafenib to induce ABCC5 expression. Sorafenib AKT serine/threonine kinase 1 Homo sapiens