Title : Delivery of gefitinib in synergism with thymoquinone via transferrin-conjugated nanoparticle sensitizes gefitinib-resistant non-small cell lung carcinoma to control metastasis and stemness.

Pub. Date : 2021 Dec 7

PMID : 34766965






1 Functional Relationships(s)
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1 These data are self-sufficient to suggest that NP-dual-3 re-sensitizes the drug-resistant A549/GR cells to gefitinib, possibly by retrieving MET phenomena via modulation of STAT3/mir-21/Akt/PTEN/HIF1-alpha axis. Gefitinib AKT serine/threonine kinase 1 Homo sapiens