Pub. Date : 2021
PMID : 34761239
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the BPH/2 and BPN/3 mice with AAA, ERK1/2 activity was significantly increased relative to the respective baseline control (P < .05) and effectively reduced by concomitant Losartan therapy (P < .05). | Losartan | mitogen-activated protein kinase 3 | Mus musculus |
| 2 | Biaxial stretch of the VSMCs in the absence of angiotensin II demonstrated increased ERK1/2 activation (P < .05 vs static control), which was significantly inhibited by Losartan. | Losartan | mitogen-activated protein kinase 3 | Mus musculus |
| 3 | ERK1/2 activity was significantly elevated in the BPH/2 mice and after AAA induction in the normotensive and hypertensive mice but was attenuated by Losartan treatment. | Losartan | mitogen-activated protein kinase 3 | Mus musculus |