Pub. Date : 2022 Apr
PMID : 34755897
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The arachidonic acid (AA) metabolites 12-hydroperoxyeicosatetraenoyl acid (12-HpETE) and 20-hydroxyeicosatetraenoic acid (20-HETE) have emerged as potential endogenous activators of TRPV1 however, whether these lipids underlie TRPV1-mediated neurogenic inflammation remains unknown. | 20-hydroxy-5,8,11,14-eicosatetraenoic acid | transient receptor potential cation channel subfamily V member 1 | Homo sapiens |
| 2 | The arachidonic acid (AA) metabolites 12-hydroperoxyeicosatetraenoyl acid (12-HpETE) and 20-hydroxyeicosatetraenoic acid (20-HETE) have emerged as potential endogenous activators of TRPV1 however, whether these lipids underlie TRPV1-mediated neurogenic inflammation remains unknown. | 20-hydroxy-5,8,11,14-eicosatetraenoic acid | transient receptor potential cation channel subfamily V member 1 | Homo sapiens |
| 3 | KEY RESULTS: In a human cantharidin-blister model the potent TRPV1 activators 20-HETE but not 12-HETE (stable metabolite of 12-HpETE) correlated with AA levels. | 20-hydroxy-5,8,11,14-eicosatetraenoic acid | transient receptor potential cation channel subfamily V member 1 | Homo sapiens |