Pub. Date : 2021 Oct 20
PMID : 34755672
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The effects of chrysin, LPS, and their combination on the mRNA expressions of iNOS and COX-2 were detected using RT-PCR; Western blotting was performed to examine the changes in cellular expressions of p-AKT, p-PRAS40, p-mTOR, mTOR, p-P70S6k, p-S6RP and S6RP following the treatments with LPS, N-Acetyl-L-cysteine, and chrysin, alone or in combinations. | Acetylcysteine | thymoma viral proto-oncogene 1 | Mus musculus |
2 | Chrysin treatment significantly reduced the generation of endogenous ROS, and treatment with N-Acetyl-L-cysteine to eliminate intracellular ROS obviously reduced the expressions of iNOS and COX-2 (P < 0.05) and blocked the AKT/mTOR pathway (P < 0.05). | Acetylcysteine | thymoma viral proto-oncogene 1 | Mus musculus |