Pub. Date : 2022 Feb
PMID : 34755642
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Concomitantly, AngII induced an increase in ROS production that was sensitive to the NOX2 specific inhibitor gp91ds-tat (1 mumol/L). | Reactive Oxygen Species | cytochrome b-245, beta polypeptide | Mus musculus |
| 2 | AngII induced IICR in Nox2-/- AMs could be restored by addition of exogenous ROS (tert-butyl hydroperoxide, tBHP: 5 mumol/L). | Reactive Oxygen Species | cytochrome b-245, beta polypeptide | Mus musculus |
| 3 | Our data demonstrate that in AMs the InsP3R is under dual control of agonist induced InsP3 and ROS formation and suggest that InsP3 and NOX2-derived ROS co-regulate atrial IICR and ECC in a defined InsP3R/NOX2 signaling domain. | Reactive Oxygen Species | cytochrome b-245, beta polypeptide | Mus musculus |
| 4 | Our data demonstrate that in AMs the InsP3R is under dual control of agonist induced InsP3 and ROS formation and suggest that InsP3 and NOX2-derived ROS co-regulate atrial IICR and ECC in a defined InsP3R/NOX2 signaling domain. | Reactive Oxygen Species | cytochrome b-245, beta polypeptide | Mus musculus |