Title : Scutellarin Reduces Cerebral Ischemia Reperfusion Injury Involving in Vascular Endothelium Protection and PKG Signal.

Pub. Date : 2021 Dec

PMID : 34750765






3 Functional Relationships(s)
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1 In conclusion, our findings suggested that SCU possesses the ability of protecting brain cells against CIR injury through vascular endothelium protection and PKG signal. scutellarin corepressor interacting with RBPJ, 1 Rattus norvegicus
2 The brain slice staining test in rats" model of middle cerebral artery occlusion (MCAO) induced CIR proved that the administration of SCU (45, 90 mg/kg, iv) significantly reduced the area of cerebral infarction. scutellarin corepressor interacting with RBPJ, 1 Rattus norvegicus
3 The Western blot assay result showed that SCU (45 mg/kg, iv) increased brain PKG activity and PKG protein level after CIR surgery. scutellarin corepressor interacting with RBPJ, 1 Rattus norvegicus