Title : Oxymatrine promotes hypertrophic scar repair through reduced human scar fibroblast viability, collagen and induced apoptosis via autophagy inhibition.

Pub. Date : 2021 Nov 8

PMID : 34749441






1 Functional Relationships(s)
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1 In vivo studies showed that inhibition of autophagy by oxymatrine promoted scar repair, resulting in a significantly improved final outcome of the hypertrophic scars, a smaller scar area, decreased epidermal and dermal thickness, and a significant downregulation of CK10, P63, collagen I, alpha-SMA, and TGF-beta1. oxymatrine keratin 10 Homo sapiens