Pub. Date : 2021 Dec
PMID : 34742922
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Prochlorperazine enhances radiosensitivity of non-small cell lung carcinoma by stabilizing GDP-bound mutant KRAS conformation. | Guanosine Diphosphate | Kirsten rat sarcoma viral oncogene homolog | Mus musculus |
| 2 | PCZ binds to the GTP-binding pocket of KRAS-mutant protein and inhibits its constitutive activation by stabilizing the GDP-bound conformation of K-Ras mutants by 9 kcal/mol compared to WT. | Guanosine Diphosphate | Kirsten rat sarcoma viral oncogene homolog | Mus musculus |
| 3 | PCZ binds to the GTP-binding pocket of KRAS-mutant protein and inhibits its constitutive activation by stabilizing the GDP-bound conformation of K-Ras mutants by 9 kcal/mol compared to WT. | Guanosine Diphosphate | Kirsten rat sarcoma viral oncogene homolog | Mus musculus |