Title : Concordance of BRCA mutation detection in tumor versus blood, and frequency of bi-allelic loss of BRCA in tumors from patients in the phase III SOLO2 trial.

Pub. Date : 2021 Dec

PMID : 34742578






1 Functional Relationships(s)
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1 Near 100% rates of bi-allelic loss of BRCA in platinum-sensitive relapsed ovarian tumors suggest routine testing for BRCA zygosity is not required in this population and reflects BRCA loss being a driver of tumorigenesis. Platinum BRCA1 DNA repair associated Homo sapiens