Title : Molecular mimicry: HUWE1 binds an atypical site in MIZ1 by adopting a typical BTB fold.

Pub. Date : 2021 Nov 4

PMID : 34739823






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 describe an exposed binding site in the MIZ1 BTB domain due to an atypical flexible region within the BTB core. btb zinc finger and BTB domain containing 17 Homo sapiens
2 This site allows HECT-type ubiquitin ligase 1 to bind the MIZ1 homodimer by forming beta strands and completing the canonical BTB fold. btb zinc finger and BTB domain containing 17 Homo sapiens