Title : Mangiferin Ameliorates HFD-Induced NAFLD through Regulation of the AMPK and NLRP3 Inflammasome Signal Pathways.

Pub. Date : 2021

PMID : 34734090






4 Functional Relationships(s)
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1 Western blot results showed that Man upregulated p-AMPKalpha levels and exhibited a significant AMPK activation effect, which was blocked by compound C. At the same time, Man downregulated the expression of NLRP3 inflammasome-related proteins and inhibited the activation of NLRP3 inflammasome, alleviating cell pyroptosis and inflammation effects. mangiferin NLR family pyrin domain containing 3 Homo sapiens
2 Western blot results showed that Man upregulated p-AMPKalpha levels and exhibited a significant AMPK activation effect, which was blocked by compound C. At the same time, Man downregulated the expression of NLRP3 inflammasome-related proteins and inhibited the activation of NLRP3 inflammasome, alleviating cell pyroptosis and inflammation effects. mangiferin NLR family pyrin domain containing 3 Homo sapiens
3 Western blot results showed that Man upregulated p-AMPKalpha levels and exhibited a significant AMPK activation effect, which was blocked by compound C. At the same time, Man downregulated the expression of NLRP3 inflammasome-related proteins and inhibited the activation of NLRP3 inflammasome, alleviating cell pyroptosis and inflammation effects. mangiferin NLR family pyrin domain containing 3 Homo sapiens
4 Western blot results showed that Man upregulated p-AMPKalpha levels and exhibited a significant AMPK activation effect, which was blocked by compound C. At the same time, Man downregulated the expression of NLRP3 inflammasome-related proteins and inhibited the activation of NLRP3 inflammasome, alleviating cell pyroptosis and inflammation effects. mangiferin NLR family pyrin domain containing 3 Homo sapiens