Title : Discovery of Hydroxybenzothiazole Urea Compounds as Multitargeted Agents Suppressing Major Cytotoxic Mechanisms in Neurodegenerative Diseases.

Pub. Date : 2021 Nov 17

PMID : 34726394






1 Functional Relationships(s)
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1 In general, the diversification of the benzylamide moiety led to an enhanced selectivity over the most homologous isoform, Dyrk1B, which was a meaningful indicator, as the high selectivity could be confirmed in an extended selectivity profiling of 3b and 16b. beclamide dual specificity tyrosine phosphorylation regulated kinase 1B Homo sapiens