Title : Metallodrug Profiling against SARS-CoV-2 Target Proteins Identifies Highly Potent Inhibitors of the S/ACE2 interaction and the Papain-like Protease PLpro.

Pub. Date : 2021 Dec 20

PMID : 34714566






1 Functional Relationships(s)
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1 Based on previous results, we have selected more than 100 structurally diverse metal complexes for a profiling as inhibitors of two relevant SARS-CoV-2 replication mechanisms, namely the interaction of the spike protein with the ACE2 receptor and the papain-like protease PL pro . Metals surface glycoprotein Severe acute respiratory syndrome coronavirus 2