Pub. Date : 2022 Jan 1
PMID : 34699919
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Lycopene mitigates DEHP-induced hepatic mitochondrial quality control disorder via regulating SIRT1/PINK1/mitophagy axis and mitochondrial unfolded protein response. | Diethylhexyl Phthalate | sirtuin 1 | Mus musculus |
| 2 | Furthermore, LYC alleviated DEHP-induced mitochondrial biogenesis disorder by suppressing SIRT1-PGC-1alpha axis, PINK1-mediated mitophagy and the activation of mitochondrial unfolded protein response (UPRmt). | Diethylhexyl Phthalate | sirtuin 1 | Mus musculus |
| 3 | This research suggested that LYC could prevent DEHP-induced hepatic mitochondrial quality control disorder via regulating SIRT1/PINK1/mitophagy axis and UPRmt. | Diethylhexyl Phthalate | sirtuin 1 | Mus musculus |