Pub. Date : 2021 Dec
PMID : 34678694
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Bixin protects mice against bronchial asthma though modulating PI3K/Akt pathway. | bixin | thymoma viral proto-oncogene 1 | Mus musculus |
| 2 | Importantly, Bixin antagonized activation of phosphatidylinositol 3-kinase/protein kinase B (PI3K/Akt) pathway both in vitro and in vivo. | bixin | thymoma viral proto-oncogene 1 | Mus musculus |
| 3 | Above all, our findings reveal that Bixin functions as a potent antagonist of PI3K/Akt signaling to protect against allergic asthma, highlighting a novel strategy for asthma treatment based on natural products. | bixin | thymoma viral proto-oncogene 1 | Mus musculus |