Title : Effects and underlying cellular pathway involved in the impairment of the neurovascular unit following exposure of adult male mice to low doses of di(2-ethylhexyl) phthalate alone or in an environmental phthalate mixture.

Pub. Date : 2022 May 1

PMID : 34678253






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Protein levels of AR but not of ERalpha were reduced in cerebral capillaries after phthalate exposure. phthalic acid androgen receptor Mus musculus
2 Altogether, the data suggest that environmental exposure to endocrine disruptors such as phthalates, could alter AR/Cav-1 interaction, impacting a Cav-1/nitric oxide/MMP pathway. phthalic acid androgen receptor Mus musculus