Pub. Date : 2021
PMID : 34659643
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In addition, phosphatidyl-3-kinase (PI3K)/AKT signaling in neurons was inhibited after exposure to bupivacaine. | Bupivacaine | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | After PI3K/AKT signaling was inhibited, bupivacaine-mediated DNA damage was further aggravated, and the expression of XPD was further upregulated. | Bupivacaine | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | In conclusion, the repair enzyme XPD, which was partially regulated by PI3K/AKT signaling, responded to bupivacaine-mediated neuronal DNA damage. | Bupivacaine | AKT serine/threonine kinase 1 | Homo sapiens |