Pub. Date : 2021 Oct 16
PMID : 34656115
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The relation between miR-140-3p and SNHG12 and the relations among HuR, SNHG12, and FAM83B were analyzed. | mir-140-3p | small nucleolar RNA host gene 12 | Homo sapiens |
| 2 | miR-140-3p directly bound to SNHG12 in GC tissues and downregulated SNHG12 expression. | mir-140-3p | small nucleolar RNA host gene 12 | Homo sapiens |
| 3 | miR-140-3p directly bound to SNHG12 in GC tissues and downregulated SNHG12 expression. | mir-140-3p | small nucleolar RNA host gene 12 | Homo sapiens |
| 4 | Overexpression of SNHG12 or FAM83B reduced the inhibition of overexpression of miR-140-3p on GC. | mir-140-3p | small nucleolar RNA host gene 12 | Homo sapiens |
| 5 | CONCLUSION: miR-140-3p directly bound to SNHG12 in GC and down-regulated the expression of SNHG12, reduced the binding of SNHG12 and HuR, thus inhibiting the nuclear transportation of HuR and the binding of HuR and FAM83B, and reducing the transcription of FAM83B, and finally inhibiting the growth and metastasis of GC. | mir-140-3p | small nucleolar RNA host gene 12 | Homo sapiens |
| 6 | CONCLUSION: miR-140-3p directly bound to SNHG12 in GC and down-regulated the expression of SNHG12, reduced the binding of SNHG12 and HuR, thus inhibiting the nuclear transportation of HuR and the binding of HuR and FAM83B, and reducing the transcription of FAM83B, and finally inhibiting the growth and metastasis of GC. | mir-140-3p | small nucleolar RNA host gene 12 | Homo sapiens |
| 7 | CONCLUSION: miR-140-3p directly bound to SNHG12 in GC and down-regulated the expression of SNHG12, reduced the binding of SNHG12 and HuR, thus inhibiting the nuclear transportation of HuR and the binding of HuR and FAM83B, and reducing the transcription of FAM83B, and finally inhibiting the growth and metastasis of GC. | mir-140-3p | small nucleolar RNA host gene 12 | Homo sapiens |