Title : Sulfiredoxin-1 protects retinal ganglion cells from high glucose-induced oxidative stress and inflammatory injury by potentiating Nrf2 signaling via the Akt/GSK-3β pathway.

Pub. Date : 2021 Dec

PMID : 34653733






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The up-regulation of Srxn1 markedly decreased HG-evoked apoptosis, reactive oxygen species (ROS) generation and pro-inflammatory cytokine release in RGCs. Reactive Oxygen Species sulfiredoxin 1 Homo sapiens
2 The up-regulation of Srxn1 markedly decreased HG-evoked apoptosis, reactive oxygen species (ROS) generation and pro-inflammatory cytokine release in RGCs. Reactive Oxygen Species sulfiredoxin 1 Homo sapiens