Title : Which proteinase-activated receptor-1 antagonist is better?: Evaluation of vorapaxar and parmodulin-2 effects on human left internal mammary artery endothelial function.

Pub. Date : 2021 Dec 1

PMID : 34653426






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Previously, vorapaxar, a proteinase-activated receptor-1 antagonist, was shown to cause endothelial damage in a cell culture study. vorapaxar coagulation factor II thrombin receptor Homo sapiens
2 CONCLUSION: Parmodulin-2 may be a better option than vorapaxar in treating cardiovascular diseases since it can inhibit PAR-1 without caused endothelial dysfunction. vorapaxar coagulation factor II thrombin receptor Homo sapiens