Pub. Date : 2021 Sep 30
PMID : 34638401
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We analyzed miRNA expression profiles in sorafenib-resistant HCC cell lines (PLC/PRF5-R1/R2) and parental cell lines (PLC/PRF5) to identify the miRNAs responsible for resistance. | Sorafenib | heparan sulfate proteoglycan 2 | Homo sapiens |
| 2 | Among them, miR-125b-5p mimic-transfected PLC/PRF5 cells (PLC/PRF5-miR125b) and showed a significantly higher IC50 for sorafenib compared with controls, while the other miRNA mimics did not. | Sorafenib | heparan sulfate proteoglycan 2 | Homo sapiens |