Title : NUDT15 polymorphism and NT5C2 and PRPS1 mutations influence thiopurine sensitivity in acute lymphoblastic leukaemia cells.

Pub. Date : 2021 Nov

PMID : 34636169






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 NUDT15 polymorphism and NT5C2 and PRPS1 mutations influence thiopurine sensitivity in acute lymphoblastic leukaemia cells. 2-mercaptopyrazine 5'-nucleotidase, cytosolic II Homo sapiens
2 It has also been demonstrated that acquired somatic mutations of the NT5C2 and PRPS1 genes, which are involved in thiopurine metabolism, are detectable in a portion of relapsed childhood ALL. 2-mercaptopyrazine 5'-nucleotidase, cytosolic II Homo sapiens