Title : Aberrant expression of PI3K/AKT signaling is involved in apoptosis resistance of hepatocellular carcinoma.

Pub. Date : 2021

PMID : 34632072






1 Functional Relationships(s)
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1 Also, perversely upregulated PI3K/AKT signaling Huh7 cells are highly resistant to treatment with chemotherapy drugs (docetaxel and sorafenib) and acquired apoptosis resistance through downregulation of tumor suppressor protein PTEN (phosphatase and tensin homolog deleted on chromosome ten). Sorafenib AKT serine/threonine kinase 1 Homo sapiens