Title : Role of Matrix Metalloproteinases in Myelin Abnormalities and Mechanical Allodynia in Rodents with Diabetic Neuropathy.

Pub. Date : 2021 Oct

PMID : 34631222






2 Functional Relationships(s)
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1 Here, we report that the gelatinases MMP-9 and MMP-2 play a critical role in axonal demyelination and DNP in rodents. dnp matrix metallopeptidase 2 Mus musculus
2 MMP-9 may contribute to streptozotocin (STZ)-induced DNP via inducing axonal demyelination and spinal central sensitization, while MMP-2 may serve as a negative regulator. dnp matrix metallopeptidase 2 Mus musculus