Title : Effect of metformin treatment on memory and hippocampal neurogenesis decline correlated with oxidative stress induced by methotrexate in rats.

Pub. Date : 2021 Dec

PMID : 34628167






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1 These results demonstrate that metformin can improve memory impairments, increase BDNF, DCX and Nrf2 protein expressions and antioxidant capacities, and decrease MDA levels in MTX-treated rats. Metformin doublecortin Rattus norvegicus