Title : Mulberry leaves ameliorate diabetes via regulating metabolic profiling and AGEs/RAGE and p38 MAPK/NF-κB pathway.

Pub. Date : 2022 Jan 30

PMID : 34626776






1 Functional Relationships(s)
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1 Furthermore, 1-deoxynojirimycin and isoquercitrin both could increase glucose uptake and promote differentiation of HepG2 cells, increase PPARgamma, C/EBPalpha and SREBP-l expression in 3T3-L1 cells, and inhibit AGEs-induced injury and apoptosis in GLUTag cells, reduce the expression of proteins related to AGEs/RAGE and p38MAPK/NF-kappaB pathway. 1-DEOXYNOJIRIMYCIN CCAAT enhancer binding protein alpha Homo sapiens