Pub. Date : 2021 Oct 8
PMID : 34622801
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We developed an efficient strategy to screen for modulators of beta-glucocerebrosidase (GCase), a lysosomal enzyme that exhibits decreased activity in patients with PD, leading to accumulation of the substrate glucosylceramide and oxidized dopamine and alpha-synuclein, which contribute to PD pathogenesis. | Glucosylceramides | glucosidase, beta, acid | Mus musculus |