Pub. Date : 2021
PMID : 34621175
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Therapeutic Potential of the Cyclin-Dependent Kinase Inhibitor Flavopiridol on c-Myc Overexpressing Esophageal Cancer. | alvocidib | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 2 | We therefore investigated whether exploiting elevated c-Myc expression is effective in treating esophageal cancer with the CDK inhibitor flavopiridol. | alvocidib | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 3 | Esophageal cancer cells with elevated c-Myc expression were found preferentially more sensitive to induction of apoptosis by the CDK inhibition flavopiridol compared to esophageal cancer cells with lower c-Myc expression. | alvocidib | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 4 | These results indicate that aggressive esophageal cancer cells with elevated c-Myc expression are sensitive to the CDK inhibitor flavopiridol, and that flavopiridol alone or in combination can be a potential therapy for c-Myc overexpressing esophageal cancer. | alvocidib | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 5 | These results indicate that aggressive esophageal cancer cells with elevated c-Myc expression are sensitive to the CDK inhibitor flavopiridol, and that flavopiridol alone or in combination can be a potential therapy for c-Myc overexpressing esophageal cancer. | alvocidib | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 6 | These results indicate that aggressive esophageal cancer cells with elevated c-Myc expression are sensitive to the CDK inhibitor flavopiridol, and that flavopiridol alone or in combination can be a potential therapy for c-Myc overexpressing esophageal cancer. | alvocidib | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |