Pub. Date : 2021 Nov 1
PMID : 34607979
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Consistently, the overexpression of LKB1 in HeLa cancer cells prevented metformin-triggered apoptosis while LKB1 knockdown significantly increased apoptosis in HEC-1-A and KLE cancer cells. | Metformin | serine/threonine kinase 11 | Homo sapiens |
| 2 | Taken together, these findings indicate an underlying biological/physiological molecular function specifically for metformin-triggered apoptosis dependent on the presence of the LKB1 gene in tumorigenesis. | Metformin | serine/threonine kinase 11 | Homo sapiens |