Title : Regulating immune memory and reversing tumor thermotolerance through a step-by-step starving-photothermal therapy.

Pub. Date : 2021 Sep 30

PMID : 34593005






1 Functional Relationships(s)
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1 METHODS: Metformin (Met) down-regulates NADH/NADPH, promotes the FAO of CD8+ T cells by activating AMPK, increases the number of CD8+ TCM, which boosts the long-term immune memory of tumor-bearing mice treated with PTT. Metformin protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus