Pub. Date : 2021 Oct
PMID : 34592836
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Targeted delivery of doxorubicin through CD44 aptamer to cancer cells. | Doxorubicin | CD44 molecule (Indian blood group) | Homo sapiens |
| 2 | Aim: The current investigation is focused on the targeted delivery of doxorubicin through CD44-aptamer-mediated active targeting to the human breast cancer cells. | Doxorubicin | CD44 molecule (Indian blood group) | Homo sapiens |
| 3 | Methods: CD44-aptamer-doxorubicin (Apt-Dox) conjugates were developed by incubating different molar ratios of aptamer and doxorubicin. | Doxorubicin | CD44 molecule (Indian blood group) | Homo sapiens |
| 4 | Methods: CD44-aptamer-doxorubicin (Apt-Dox) conjugates were developed by incubating different molar ratios of aptamer and doxorubicin. | Doxorubicin | CD44 molecule (Indian blood group) | Homo sapiens |
| 5 | Methods: CD44-aptamer-doxorubicin (Apt-Dox) conjugates were developed by incubating different molar ratios of aptamer and doxorubicin. | Doxorubicin | CD44 molecule (Indian blood group) | Homo sapiens |
| 6 | Apt-Dox conjugate selectively internalized and accumulated in CD44-overexpressing cells. | Doxorubicin | CD44 molecule (Indian blood group) | Homo sapiens |
| 7 | Conclusion: Apt-Dox conjugate selectively delivers doxorubicin to CD44-expressing cancer cells, thereby inhibiting selective cell proliferation and enhancing the targeted therapy. | Doxorubicin | CD44 molecule (Indian blood group) | Homo sapiens |
| 8 | Conclusion: Apt-Dox conjugate selectively delivers doxorubicin to CD44-expressing cancer cells, thereby inhibiting selective cell proliferation and enhancing the targeted therapy. | Doxorubicin | CD44 molecule (Indian blood group) | Homo sapiens |