Title : Regulatory role of microRNA-320 during off-pump coronary artery bypass grafting with dexmedetomidine adjunct anesthesia.

Pub. Date : 2021 Nov

PMID : 34584546






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1 The present study investigated the effects of dexmedetomidine on the expression level of microRNA-320 (miR-320) and neuroglobin (NGB) in patients undergoing off-pump coronary artery bypass grafting (OPCABG). Dexmedetomidine neuroglobin Homo sapiens
2 The present study investigated the effects of dexmedetomidine on the expression level of microRNA-320 (miR-320) and neuroglobin (NGB) in patients undergoing off-pump coronary artery bypass grafting (OPCABG). Dexmedetomidine neuroglobin Homo sapiens
3 Compared with control subjects, patients in the dexmedetomidine group had higher NGB levels in the blood. Dexmedetomidine neuroglobin Homo sapiens
4 Pre-administration of dexmedetomidine can decrease miR-320 expression level in the blood of patients undergoing OPCABG, stimulating the high expression of NGB and increasing the proliferation activity of neuronal cells, which may decrease the postoperative cognitive impairment. Dexmedetomidine neuroglobin Homo sapiens