Pub. Date : 2021 Sep 15
PMID : 34573100
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Huntington"s disease (HD) is caused by expansion of polyglutamine repeats in the protein huntingtin, which affects the corpus striatum of the brain. | polyglutamine | huntingtin | Homo sapiens |
2 | The polyglutamine repeats in mutant huntingtin cause its aggregation and elicit toxicity by affecting several cellular processes, which include dysregulated organellar stress responses. | polyglutamine | huntingtin | Homo sapiens |