Title : Signaling Overlap between the Golgi Stress Response and Cysteine Metabolism in Huntington's Disease.

Pub. Date : 2021 Sep 15

PMID : 34573100






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Huntington"s disease (HD) is caused by expansion of polyglutamine repeats in the protein huntingtin, which affects the corpus striatum of the brain. polyglutamine huntingtin Homo sapiens
2 The polyglutamine repeats in mutant huntingtin cause its aggregation and elicit toxicity by affecting several cellular processes, which include dysregulated organellar stress responses. polyglutamine huntingtin Homo sapiens