Pub. Date : 2021
PMID : 34568577
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Scutellarin-induced A549 cell apoptosis depends on activation of the transforming growth factor-beta1/smad2/ROS/caspase-3 pathway. | scutellarin | caspase 3 | Homo sapiens |
| 2 | Moreover, scutellarin-induced intracellular ROS production and cleaved caspase-3 expression were inhibited by blocking the TGF-beta1/smad2 pathway with SB431542. | scutellarin | caspase 3 | Homo sapiens |
| 3 | Our study indicated that scutellarin induced A549 cell apoptosis via the TGF-beta1/smad2/ROS/caspase-3 pathway. | scutellarin | caspase 3 | Homo sapiens |