Pub. Date : 2022 Mar 3
PMID : 34562089
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | DOX activates nicotinamide adenine dinucleotide phosphate NADPH oxidase (NOX) in the heart, resulting in excessive reactive oxygen species that can induce cardiomyocyte apoptosis through phosphorylation of p53, DNA damage and/or mitogen-activated protein kinases-mediated cardiomyocyte apoptosis. | Oxygen | tumor protein p53 | Homo sapiens |