Pub. Date : 2021
PMID : 34557491
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Protective Mechanism of Luteinizing Hormone and Follicle-Stimulating Hormone Against Nicotine-Induced Damage of Mouse Early Folliculogenesis. | Nicotine | follicle stimulating hormone beta | Mus musculus |
2 | In this paper, we discovered that luteinizing hormone (LH) and follicle-stimulating hormone (FSH) could counteract the damage caused by nicotine of mouse germ cell cyst breakdown. | Nicotine | follicle stimulating hormone beta | Mus musculus |
3 | In this paper, we discovered that luteinizing hormone (LH) and follicle-stimulating hormone (FSH) could counteract the damage caused by nicotine of mouse germ cell cyst breakdown. | Nicotine | follicle stimulating hormone beta | Mus musculus |
4 | Compared with the nicotine group, the quality of oocytes and the number of follicles were remarkably increased in the nicotine plus LH group or nicotine plus FSH group. | Nicotine | follicle stimulating hormone beta | Mus musculus |
5 | LH and FSH could alleviate nicotine-induced oocyte autophagy by different pathways. | Nicotine | follicle stimulating hormone beta | Mus musculus |
6 | LH reduced the nicotine-induced autophagy by restoring the phosphorylation level of adenosine 5"-monophosphate-activated protein kinase alpha-1, while FSH by downregulating the phosphorylation level of Forkhead box class O 1. | Nicotine | follicle stimulating hormone beta | Mus musculus |
7 | Taken together, these results suggested that LH and FSH could counteract the damage caused by nicotine and finally ensure normal germ cell cyst breakdown and early embryo development. | Nicotine | follicle stimulating hormone beta | Mus musculus |