Pub. Date : 2022 Mar
PMID : 34551150
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The objective of this study was to clarify the role of melatonin in cisplatin-induced cytotoxicity in CD44high OSCC cells. | Cisplatin | CD44 molecule (Indian blood group) | Homo sapiens |
| 2 | Mesenchymal-like CD44high OSCC cells demonstrated strong resistance to cisplatin-induced cell death compared with epithelial-like CD44high OSCC cells. | Cisplatin | CD44 molecule (Indian blood group) | Homo sapiens |
| 3 | These results suggest that melatonin-induced miR-181c-5p enhances cisplatin-induced cell death through inhibition of DERL1 in mesenchymal-like CD44high cells. | Cisplatin | CD44 molecule (Indian blood group) | Homo sapiens |
| 4 | CONCLUSIONS: Melatonin plays a vital role in promoting cisplatin-induced cytotoxicity in mesenchymal like-CD44high OSCC cells. | Cisplatin | CD44 molecule (Indian blood group) | Homo sapiens |