Title : SPHK1 contributes to cisplatin resistance in bladder cancer cells via the NONO/STAT3 axis.

Pub. Date : 2021 Nov

PMID : 34549307






1 Functional Relationships(s)
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1 The results revealed that SPHK1 was positively correlated with cisplatin resistance in bladder cancer cells, exhibiting an antiapoptotic effect that was reflected by the downregulation of apoptosis-related proteins (Bax and cleaved caspase-3) and the upregulation of an antiapoptotic protein (Bcl-2) in SPHK1-overexpression cell lines. Cisplatin caspase 3 Homo sapiens