Title : Solvent-controlled two-step one-pot syntheses of α-X (X = Br or Cl) enamino ketones/esters and 3-(2,5-dioxopyrrolidin-1-yl)acrylate by using terminal carbonyl alkynes.

Pub. Date : 2021 Sep 22

PMID : 34549232






1 Functional Relationships(s)
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1 A new two-step one-pot aminobromination/chlorination of carbonyl alkynes has been achieved via a Michael addition of aliphatic secondary amines and subsequent beta-bromination/chlorination of the obtained enamines to afford various alpha-X (X = Br or Cl) enamino ketones/esters in moderate to good yields. enamines chromosome 12 open reading frame 73 Homo sapiens