Pub. Date : 2021 Sep 21
PMID : 34548471
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | ASXL1 mutations are associated with distinct epigenomic alterations that lead to sensitivity to venetoclax and azacytidine. | venetoclax | ASXL transcriptional regulator 1 | Homo sapiens |
| 2 | To explore the mechanisms underlying the selective sensitivity of mutant leukemia cells to VEN and AZA, we used cell-based isogenic models containing a common leukemia-associated mutation in the epigenetic regulator ASXL1. | venetoclax | ASXL transcriptional regulator 1 | Homo sapiens |