Title : SREBP1-induced fatty acid synthesis depletes macrophages antioxidant defences to promote their alternative activation.

Pub. Date : 2021 Sep

PMID : 34531575






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Mechanistically, DNL consumes NADPH, partitioning it away from cellular antioxidant defences and raising reactive oxygen species levels. Reactive Oxygen Species 2,4-dienoyl-CoA reductase 1 Homo sapiens