Title : Bortezomib enhances the anti-cancer effect of the novel Bruton's tyrosine kinase inhibitor (BGB-3111) in mantle cell lymphoma expressing BTK.

Pub. Date : 2021 Sep 10

PMID : 34508613






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 BGB-3111 provides better safety than another BTK inhibitor, ibrutinib as ibrutinib inhibits the inducible T-cell kinase (ITK) as an off-target effect but BGB-3111 does not inhibit ITK. ibrutinib IL2 inducible T cell kinase Homo sapiens
2 BGB-3111 provides better safety than another BTK inhibitor, ibrutinib as ibrutinib inhibits the inducible T-cell kinase (ITK) as an off-target effect but BGB-3111 does not inhibit ITK. ibrutinib IL2 inducible T cell kinase Homo sapiens
3 BGB-3111 provides better safety than another BTK inhibitor, ibrutinib as ibrutinib inhibits the inducible T-cell kinase (ITK) as an off-target effect but BGB-3111 does not inhibit ITK. ibrutinib IL2 inducible T cell kinase Homo sapiens
4 BGB-3111 provides better safety than another BTK inhibitor, ibrutinib as ibrutinib inhibits the inducible T-cell kinase (ITK) as an off-target effect but BGB-3111 does not inhibit ITK. ibrutinib IL2 inducible T cell kinase Homo sapiens