Title : Imidazopyridazine Acetylcholinesterase Inhibitors Display Potent Anti-Proliferative Effects in the Human Neuroblastoma Cell-Line, IMR-32.

Pub. Date : 2021 Sep 1

PMID : 34500749






1 Functional Relationships(s)
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1 Two of these substituted 3-nitro-6-amino-imidazo(1,2-b)pyridazine compounds (5c and 5h) showed potent acetylcholinesterase (AChE) inhibitory activity (IC50 40-50 nM), which we have previously reported. 5h acetylcholinesterase (Cartwright blood group) Homo sapiens