Title : Dipeptidyl peptidase-4 (DPP4) inhibitor sitagliptin alleviates liver inflammation of diabetic mice by acting as a ROS scavenger and inhibiting the NFκB pathway.

Pub. Date : 2021 Sep 7

PMID : 34493714






1 Functional Relationships(s)
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1 Moreover, sitagliptin reduced TNFalpha or LPS-induced cellular reactive oxygen species (ROS) level, cell apoptosis, and protein expression in the NFkappaB signaling pathway in HepG2 cells or primary mouse hepatocytes. Sitagliptin Phosphate tumor necrosis factor Homo sapiens