Title : The effects of selected inhibitors on human fetal adrenal steroidogenesis differs under basal and ACTH-stimulated conditions.

Pub. Date : 2021 Sep 8

PMID : 34493283






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1 RESULTS: Treatment with Abiraterone acetate and Osilodrostat resulted in potent inhibition of CYP17A1 and CYP11B1/2, respectively, while treatment with Efavirenz reduced testosterone secretion under basal conditions. Abiraterone Acetate cytochrome P450 family 11 subfamily B member 1 Homo sapiens