Title : HGF/c-MET pathway contributes to cisplatin-mediated PD-L1 expression in hepatocellular carcinoma.

Pub. Date : 2021 Dec

PMID : 34486197






2 Functional Relationships(s)
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1 In the present study, we found that the expression of HGF, p-Akt, p-ERK, and PD-L1 was increased in cisplatin-treated SNU-368 and SNU-739 cells. 4-(1H-Pyrrol-1-yl)aniline CD274 molecule Homo sapiens
2 Moreover, Inhibition of HGF/c-MET, PI3K/Akt, and MEK/ERK signaling pathways can dramatically block cisplatin or HGF-induced PD-L1 expression in SNU-368 and SNU-739 cells. 4-(1H-Pyrrol-1-yl)aniline CD274 molecule Homo sapiens