Title : Arsenic trioxide targets Hsp60, triggering degradation of p53 and survivin.

Pub. Date : 2021 Aug 18

PMID : 34476069






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Arsenic trioxide targets Hsp60, triggering degradation of p53 and survivin. Arsenic Trioxide tumor protein p53 Homo sapiens
2 Significantly, the binding of ATO to Hsp60 disrupts the formation of Hsp60-p53 and Hsp60-survivin complexes, resulting in degradation of p53 and survivin. Arsenic Trioxide tumor protein p53 Homo sapiens
3 Significantly, the binding of ATO to Hsp60 disrupts the formation of Hsp60-p53 and Hsp60-survivin complexes, resulting in degradation of p53 and survivin. Arsenic Trioxide tumor protein p53 Homo sapiens